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2016 In-line Monitoring of Monomer and Polymer Content During Microgel Synthesis Using Precipitation Polymerization via Raman Spectroscopy and Indirect Hard Modeling
  Indirect Hard Modeling (IHM) enables the quantitative analysis during microgel synthesis with Raman spectroscopy, having a model which is robust against changes in microgel particle size and temperature.
  DOI: 10.1177/0003702815626663
2015 Model-Based Recognition of Mid-Infrared Sensor Fouling in Paracetamol Crystallization
  API deposition on a fibre-optic ATR immersion probe for MIR spectroscopy is detected in a crystallization process, applying an intelligent Indirect Hard Modeling (IHM) approach for spectral analysis.
  DOI: 10.1002/ceat.201400585
2015 Automated data evaluation and modelling of simultaneous 19F– 1H medium-resolution NMR spectra for online reaction monitoring
  Benchtop NMR instruments are applied as online process analysers for the monitoring of reacting mixtures. Essential contribution of Indirect Hard Modeling to quantitative Data Analysis.
  DOI: 10.1002/mrc.4216
2013 Application of ATR-MIR Spectroscopy in the Pilot Plant – Scope and Limitations using the Example of Paracetamol Crystallizations
  MIR spectroscopic monitoring of an API crystallisation; successful method transfer from lab to pilot plant scale and compensation of perturbations through Indirect Hard Modeling.
  DOI: 10.1016/j.cep.2013.04.003
2013 Comprehensive monitoring of a biphasic switchable solvent synthesis
  MIR and UV spectroscopic monitoring of a high pressure synthesis with simultaneous measurements in both active phases.
  DOI: 10.1039/c2an36044f
2012 Concentration Measurements in Ionic Liquid–Water Mixtures by Mid-Infrared Spectroscopy and Indirect Hard Modeling
  Quantitative characterization of binary mixtures of water and ionic liquids using Mid-IR spectroscopy in combination with Indirect Hard Modeling.
  DOI: 10.1366/11-06427
2011 Diffusion of poly(ethylene glycol) and ectoine in NIPAAm hydrogels with confocal Raman spectroscopy
  Characterisation of diffusion in hydrogels by measuring time- and space-resolved concentration profiles using confocal Raman spectroscopy
  DOI: 10.1007/s00396-011-2399-7
2010 Bridging the gap: A nested-pipe reactor for slow reactions in continuous flow chemical synthesis
  Characterisation of a novel pilot-scale reactor for continuous production of Fine Chemicals
  DOI: 10.1016/j.cej.2010.09.004
2009 Determination of the Dispersion Characteristics of Miniaturized Coiled Reactors with Fiber-Optic Fourier Transform Mid-infrared Spectroscopy
  Characterisation of a miniaturised continuous lab reactor
  DOI: 10.1021/ie901094q
2009 An Ozonolysis-Reduction Sequence for the Synthesis of Pharmaceutical Intermediates in Microstructured Devices
  Reaction monitoring of a pharmaceutical synthesis in a microstructured device
  DOI: 10.1021/op9000669
2009 Direct determination of the concentration dependence of diffusivities using combined model-based Raman and NMR experiments
  Determination of diffusion behaviour in multi-component system with Raman and NMR spectroscopy
  DOI: 10.1016/j.fluid.2008.10.012
2008 Identification of unknown pure component spectra by indirect hard modeling
  Hard Modeling Factor Analysis (HMFA): Calibration-free spectral analysis based on Indirect Hard Modeling
  DOI: 10.1016/j.chemolab.2008.05.002
2007 In situ monitoring of an isocyanate reaction by fiber-optic FT-IR/ATR-spectroscopy
  Reaction monitoring and kinetic studies of a polyurethane synthesis
  DOI: 10.1016/j.vibspec.2006.07.004
2007 Process monitoring and control in microreactors with ATR IR Spectroscopy
  Micro-structured flow cell for miniaturised fibre optical mid-infrared sensors
  DOI: 10.1002/cite.200750089
2007 Fully automated indirect hard modeling of mixture spectra
  Automated modelling of spectra with IHM: Validation with mid-infrared and Raman spectra
  DOI: 10.1016/j.chemolab.2007.11.004
2006 Highly Flexible Fibre-Optic ATR-IR Probe for Inline Reaction Monitoring
  Applications of fibre-optical spectroscopy in organic synthesis
  DOI: 10.1021/op0601767
2006 Combining reaction calorimetry and ATR-IR spectroscopy for the operando monitoring of ionic liquids synthesis
  A combination of fibre-optical spectroscopy with reaction calorimetry
  DOI: 10.1016/j.cattod.2006.12.007
2006 Mid-infrared monitoring of gas-liquid reactions in vitamin D analog synthesis with a novel fiber optical diamond ATR sensor
  Reaction monitoring in a vitamin synthesis
  DOI: 10.1002/ceat.200600110
2006 Ternary diffusivities by model-based analysis of raman spectroscopy measurements
  Elucidation of diffusion processes in complex systems
  DOI: 10.1002/aic.11021
2005 Method for quantitative determination of spatial polymer distribution in alginate beads using Raman spectroscopy
  Raman spectroscopy for the characterisation of polymer beads
  DOI: 10.1366/0003702053585363
2004 Indirect Spectral Hard Modeling for the analysis of reacting and interacting mixtures
  Indirect Hard Modeling (IHM): New model-based method for spectral analysis
  DOI: 10.1366/0003702041655368
2004 Automatic generation of peak-shaped models
  Automatic generation of peak-shaped models: Foundation for Indirect Hard Modeling
  DOI: 10.1366/0003702041655421
2003 Novel infrared optical probes for process monitoring and analysis based on next-generation silver halide fibers
  Recent developments in optical fibres for reaction monitoring
  DOI: 10.1007/s00216-003-1782-8
2003 Model-based measurement of diffusion using Raman spectroscopy
  Monitoring of multi-component diffusion with Raman spectroscopy
  DOI: 10.1002/aic.690490205
2002 Bio-analytical applications of mid-infrared spectroscopy using silver halide fiber-optic probes
  Applications from biomedical analytics
  DOI: 10.1016/S0584-8547(02)00103-9
2001 Novel developments in mid-IR fiber-optic spectroscopy for analytical applications
  Overview over new fibre-optical sensors for mid-infrared spectroscopy
  DOI: 10.1016/S0022-2860(00)00804-8